hrp0097rfc8.6 | Fat, metabolism and obesity 2 | ESPE2023

Leukocytes and Neutrophil–Lymphocyte Ratio as Indicators of decreased insulin sensitivity in NGT Overweight and Obese Children with high 1-hour post-load plasma glucose levels

Mastromauro Concetta , Lauriola Federico , Matonti Lorena , Trisi Giulia , Chiarelli Francesco , Mohn Angelika , Giannini Cosimo

Introduction: Obese children with normal glucose tolerance (NGT) but with 1-hour post-load plasma glucose (1hPG) ≥ 132.5 mg/dl are at higher risk of developing type 2 diabetes (T2D) and cardiometabolic complications. In addition, new markers of systemic inflammation derived from blood cell count could be used as indicators of insulin resistance, thus predicting worse metabolic profile.Objective: The aim of our study w...

hrp0097p1-52 | Fat, Metabolism and Obesity | ESPE2023

Effects of Relaxation of COVID-19 restriction measurements on glucose and insulin metabolism in overweight and obesity youth

Matonti Lorena , Trisi Giulia , Mastromauro Concetta , Di Pietro Giada , Chiarelli Francesco , Giannini Cosimo , Mohn Angelika

Background: COVID-19 restriction measurements have determined profound alterations in glucose and insulin metabolism in children with overweight and obesity. However, to date few data have explored the effects of the relaxation of restrictions in the pediatric population. Thus, we compared anthropometric and OGTT data in children with overweight and obesity during the two years after (2021-2023) compared to the two years during (2020-2021) and before (2018-201...